Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24937400 | 0.84 | L3MBTL1 (0.56) | RAB9ANPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL1431721 | 0.83 | RAB9A (0.50) | RAB9ANPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL2660301 | 0.80 | MEN1 (0.51) | RAB9ANPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL262196 | 0.78 | MEN1 (0.53) | RAB9ANPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL336115 | 0.78 | KMT2A (0.53) | RAB9ANPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL21617355 | 0.77 | KMT2A (0.60) | RAB9ANPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL23361461 | 0.77 | KMT2A (0.49) | RAB9ANPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL16963334 | 0.77 | KMT2A (0.55) | RAB9ANPC1L3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL23354141 | 0.76 | MEN1 (0.48) | RAB9ANPC1L3MBTL1MEN1KMT2A | |
| SCHEMBL29158106 | 0.75 | KMT2A (0.50) | RAB9ANPC1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601192-A1 | FUSED HETEROCYCLIC COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012018909-A1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-02-09 | — | — | WO | disclosed |