Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701639 | 0.86 | TP53 (0.46) | TP53TDP1ALDH1A1TSHRTRPA1 | |
| SCHEMBL5701522 | 0.79 | ALDH1A1 (0.42) | TDP1ALDH1A1TSHRTRPA1HDAC8 | |
| SCHEMBL29434664 | 0.79 | TP53 (0.48) | TP53TDP1ALDH1A1TSHRTRPA1 | |
| SCHEMBL435537 | 0.79 | TP53 (0.48) | TP53TDP1ALDH1A1TSHRTRPA1 | |
| SCHEMBL5701614 | 0.79 | TP53 (0.42) | TP53TDP1ALDH1A1TSHRTRPA1 | |
| SCHEMBL1493173 | 0.78 | ESR1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL18017236 | 0.77 | ESR1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL10621571 | 0.77 | TP53 (0.50) | TP53TDP1ALDH1A1TSHRTRPA1 | |
| SCHEMBL18017240 | 0.77 | ESR1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL18017242 | 0.77 | ESR1 (0.32) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1510520-B1 | Preparation of branched siloxane | SHINETSU CHEMICAL CO (JP) | 2006-07-26 | — | — | EP | disclosed |
| US-6943264-B2 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL, CO., LTD. (JP) | 2005-09-13 | — | — | US | disclosed |
| US-20050049427-A1 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-03-03 | — | — | US | disclosed |
| EP-1510520-A1 | Preparation of branched siloxane | Shin-Etsu Chemical Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |