SCHEMBL5701639

SCHEMBL5701639

C=Cc1cccc([Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35
TRPA1 O75762 1/20 0.33
PTGS2 P35354 1/20 0.32
HDAC8 Q9BY41 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5701828 0.86 TP53 (0.43) TP53TDP1ALDH1A1TSHRTRPA1
SCHEMBL435537 0.81 TP53 (0.48) TP53TDP1ALDH1A1TSHRTRPA1
SCHEMBL29434664 0.81 TP53 (0.48) TP53TDP1ALDH1A1TSHRTRPA1
SCHEMBL5701614 0.81 TP53 (0.42) TP53TDP1ALDH1A1TSHRTRPA1
SCHEMBL8736695 0.81 NFE2L2 (0.43) ALDH1A1TSHRTRPA1
SCHEMBL8736691 0.81 NFE2L2 (0.43) ALDH1A1TSHRTRPA1
SCHEMBL3157051 0.79 TP53 (0.54) TP53TDP1ALDH1A1TSHRTRPA1
SCHEMBL5702032 0.77 TP53 (0.44) TP53TDP1ALDH1A1TSHRTRPA1
SCHEMBL29434580 0.77 TP53 (0.44) TP53TDP1ALDH1A1TSHRTRPA1
SCHEMBL29434674 0.77 TP53 (0.44) TP53TDP1ALDH1A1TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683790-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-01-28 EP claimed
WO-2024194826-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2024-09-26 WO claimed
US-20240316886-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2024-09-26 US claimed
US-6265499-B1 POLYMERIZING MIXTURE MENICON CO., LTD. (JP) 2001-07-24 US claimed
WO-2026105013-A1 CONTACT LENSES WITH COLOR FILTERING ZONE ALCON INC. (CH) 2026-05-21 WO disclosed
US-20260133439-A1 CONTACT LENSES WITH COLOR FILTERING ZONE ALCON INC. (CH) 2026-05-14 US disclosed
US-20260118700-A1 DIFFRACTIVE MULTIFOCAL CONTACT LENS ALCON INC (CH) 2026-04-30 US disclosed
US-20260104598-A1 COMPOSITE CONTACT LENSES WITH ULTRATHIN OBJECTS ALCON INC (CH) 2026-04-16 US disclosed
EP-4719750-A1 EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4719753-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4719751-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP disclosed
EP-4683790-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-01-28 EP disclosed
US-20050049427-A1 Preparation of branched siloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-03 US disclosed
EP-1510520-A1 Preparation of branched siloxane Shin-Etsu Chemical Co., Ltd. (JP) 2005-03-02 EP disclosed
EP-0921134-B1 Process for producing a shaped product MENICON CO LTD (JP) 2004-04-07 EP disclosed
EP-0814095-B1 Process for producing a shaped product MENICON CO LTD (JP) 2001-10-24 EP disclosed
US-6265499-B1 POLYMERIZING MIXTURE MENICON CO., LTD. (JP) 2001-07-24 US disclosed
EP-0921134-A1 Process for producing a shaped product Menicon Co., Ltd. (JP) 1999-06-09 EP disclosed
US-5866047-A Process for producing a shaped product MENICON CO., LTD. (JP) 1999-02-02 US disclosed
EP-0814095-A2 Process for producing a shaped product Menicon Co., Ltd. (JP) 1997-12-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260133439-A1 CONTACT LENSES WITH COLOR FILTERING ZONE MYO1G, STRA6, GJA1 TP53 4608/4885TDP1 3729/4885ALDH1A1 2727/4885
US-20260104598-A1 COMPOSITE CONTACT LENSES WITH ULTRATHIN OBJECTS CRYZ, CRYAA, LIMA1 TP53 2812/4885TDP1 3619/4885ALDH1A1 1922/4885
US-20260118700-A1 DIFFRACTIVE MULTIFOCAL CONTACT LENS DSG1, SDC1, DSP TP53 1936/4885TDP1 3016/4885ALDH1A1 3575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.