Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MVD | P53602 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | REN | P00797 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PEPD | P12955 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702040 | 1.00 | ACE (0.47) | ACEALDH1A1MVDLMNAREN | |
| SCHEMBL20839701 | 0.88 | ACE (0.62) | ACEMVDLMNARENHSD17B10 | |
| SCHEMBL1170836 | 0.88 | ACE (0.62) | ACEMVDLMNARENHSD17B10 | |
| SCHEMBL3200494 | 0.88 | ACE (0.62) | ACEMVDLMNARENHSD17B10 | |
| SCHEMBL3717332 | 0.86 | ACE (0.56) | ACEMVDLMNARENHSD17B10 | |
| SCHEMBL3717330 | 0.86 | ACE (0.56) | ACEMVDLMNARENHSD17B10 | |
| SCHEMBL6168040 | 0.82 | ALDH1A1 (0.41) | ALDH1A1LMNA | |
| N-Acetylproline SCHEMBL9365811 | 0.81 | ACE (0.54) | ACEMVDLMNARENHSD17B10 | |
| SCHEMBL7374901 | 0.79 | ACE (0.47) | ACEMVDLMNARENHSD17B10 | |
| SCHEMBL2770377 | 0.77 | FKBP1A (0.42) | ACEALDH1A1LMNAPEPDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974670-B1 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL CO (JP) | 2006-09-13 | — | — | EP | disclosed |
| US-6143554-A | Process for producing optically active n-substituted azetidine-2 carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0974670-A2 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-01-26 | — | — | EP | disclosed |