Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701861 | 0.87 | SRD5A1 (0.54) | SRD5A1SRD5A2RAB9ACTSVCTSL | |
| SCHEMBL5702169 | 0.85 | SRD5A1 (0.54) | SRD5A1SRD5A2CTSVCTSLRXFP1 | |
| SCHEMBL5701889 | 0.84 | SRD5A2 (0.82) | SRD5A1SRD5A2FLT3POLBNPC1 | |
| SCHEMBL5702172 | 0.81 | SRD5A1 (0.50) | SRD5A1SRD5A2POLBCTSVCTSL | |
| SCHEMBL7193910 | 0.78 | SRD5A1 (0.62) | SRD5A1SRD5A2FLT3POLBNPC1 | |
| SCHEMBL3420585 | 0.75 | FLT3 (0.54) | FLT3POLBNPC1RAB9ARXFP1 | |
| SCHEMBL3419450 | 0.75 | PDGFRB (0.60) | FLT3POLBNPC1RAB9AMEN1 | |
| SCHEMBL3243291 | 0.74 | SRD5A2 (1.00) | SRD5A1SRD5A2FLT3POLBNPC1 | |
| SCHEMBL7169748 | 0.74 | SRD5A2 (1.00) | SRD5A1SRD5A2FLT3POLBNPC1 | |
| SCHEMBL3409832 | 0.73 | ALDH1A1 (0.68) | SRD5A2FLT3SMN1; SMN2CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1302460-B1 | Indolecarboxylic compounds and their use as pharmaceutical compounds | OREAL (FR) | 2006-08-02 | — | — | EP | claimed |