Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701900 | 0.85 | SRD5A2 (0.70) | SRD5A1SRD5A2PRMT5EGFRERBB2 | |
| SCHEMBL5702169 | 0.84 | SRD5A1 (0.54) | SRD5A1SRD5A2RXFP1CTSVCTSL | |
| SCHEMBL5702136 | 0.81 | SRD5A1 (0.58) | SRD5A1SRD5A2MRGPRX4RXFP1CTSV | |
| SCHEMBL7033125 | 0.80 | S1PR1 (0.38) | PRMT5EGFRERBB2ERBB4CARM1 | |
| SCHEMBL7200219 | 0.79 | SRD5A1 (0.53) | SRD5A1SRD5A2PRMT5EGFRERBB2 | |
| SCHEMBL5701861 | 0.78 | SRD5A1 (0.54) | SRD5A1SRD5A2MRGPRX4RXFP1CTSV | |
| SCHEMBL5701947 | 0.69 | SRD5A1 (0.53) | SRD5A1SRD5A2MRGPRX4PPARGPTGER1 | |
| SCHEMBL19178802 | 0.69 | EHMT2 (0.50) | SRD5A1SRD5A2RXFP1MEN1KMT2A | |
| SCHEMBL5702163 | 0.68 | SRD5A2 (0.76) | SRD5A1SRD5A2RXFP1MEN1KMT2A | |
| SCHEMBL6260071 | 0.68 | KDM4E (0.46) | SRD5A1SRD5A2RXFP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1302460-B1 | Indolecarboxylic compounds and their use as pharmaceutical compounds | OREAL (FR) | 2006-08-02 | — | — | EP | claimed |