Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701856 | 1.00 | CYP2D6 (0.43) | CYP2D6APPCYP2C19CYP3A4CYP2C9 | |
| SCHEMBL2770703 | 0.89 | CYP3A4 (0.42) | CYP2D6APPCYP2C19CYP3A4CYP2C9 | |
| SCHEMBL5701916 | 0.72 | CYP2D6 (0.42) | CYP2D6APPCYP2C19CYP3A4CYP2C9 | |
| SCHEMBL5702210 | 0.72 | CYP2D6 (0.42) | CYP2D6APPCYP2C19CYP3A4CYP2C9 | |
| SCHEMBL2772038 | 0.70 | GAA (0.42) | CYP2D6APPCYP2C19CYP3A4CYP2C9 | |
| SCHEMBL8499616 | 0.70 | MMP2 (0.36) | CYP2D6APPCYP2C19CYP3A4CYP2C9 | |
| SCHEMBL3067553 | 0.69 | HPGD (0.43) | CYP2D6KMT2AGAAMCOLN3ALDH1A1 | |
| SCHEMBL27183064 | 0.67 | GAA (0.46) | CYP2D6KMT2AGAAMCOLN3HTT | |
| SCHEMBL4004910 | 0.67 | CYP3A4 (0.60) | CYP2D6CYP2C19CYP3A4CYP2C9KMT2A | |
| SCHEMBL8499613 | 0.67 | MMP9 (0.48) | APPHTTALDH1A1MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974670-B1 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL CO (JP) | 2006-09-13 | — | — | EP | disclosed |
| US-6143554-A | Process for producing optically active n-substituted azetidine-2 carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0974670-A2 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-01-26 | — | — | EP | disclosed |