Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260071 | 0.84 | KDM4E (0.46) | EHMT2RXFP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4706673 | 0.78 | MTNR1A (0.56) | RXFP1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL10930614 | 0.76 | MTNR1A (0.56) | KMT2AMEN1POLBKDM4EGAA | |
| SCHEMBL4708943 | 0.75 | PIN1 (0.53) | RXFP1KMT2AMEN1POLBKDM4E | |
| SCHEMBL6586200 | 0.75 | KDM4E (0.50) | SRD5A2KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL6514324 | 0.75 | RXFP1 (0.53) | EHMT2RXFP1SRD5A1SRD5A2KMT2A | |
| SCHEMBL9239615 | 0.74 | FLT3 (0.52) | RXFP1KDM4ENPSR1MAPTTDP1 | |
| SCHEMBL4707979 | 0.73 | MTNR1A (0.59) | KMT2AMEN1POLBKDM4EMAPT | |
| SCHEMBL335983 | 0.72 | SRD5A1 (0.70) | EHMT2RXFP1SRD5A1SRD5A2KMT2A | |
| SCHEMBL20135978 | 0.72 | RXFP1 (0.55) | EHMT2RXFP1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582351-B1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOLE OR INDOLINE COMPOUND, A METAL SALT, HYDROGEN PEROXIDE AND A BASIFYING AGENT | L'ORÉAL (FR) | 2017-08-02 | — | — | EP | claimed |