Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10282142 | 0.83 | ALDH1A1 (0.48) | ALDH1A1GLATSHRCNR2CNR1 | |
| SCHEMBL5702149 | 0.83 | ALDH1A1 (0.53) | ALDH1A1GLATSHRCYP3A4MEN1 | |
| SCHEMBL380050 | 0.83 | ALDH1A1 (0.76) | ALDH1A1GLATSHRCYP3A4MEN1 | |
| SCHEMBL26274433 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GLATSHRCNR2CNR1 | |
| SCHEMBL11037938 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GLATSHRCNR2CYP3A4 | |
| SCHEMBL3646180 | 0.82 | CYP3A4 (0.65) | ALDH1A1GLATSHRCNR2CNR1 | |
| SCHEMBL11084579 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GLATSHRCNR2CYP3A4 | |
| SCHEMBL915703 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GLATSHRCYP3A4MEN1 | |
| SCHEMBL250872 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GLATSHRCYP3A4MEN1 | |
| SCHEMBL1485828 | 0.82 | ALDH1A1 (0.52) | ALDH1A1GLATSHRCNR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673337-A2 | ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-06-28 | — | — | EP | claimed |
| WO-2005033066-A2 | ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2005-04-14 | — | — | WO | claimed |
| EP-1673337-A2 | ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005033066-A2 | ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2005-04-14 | — | — | WO | disclosed |