SCHEMBL5702149

SCHEMBL5702149

CCN(C(=O)O)c1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
GLA P06280 1/20 0.53
TSHR P16473 1/20 0.53
ESR1 P03372 3/20 0.46
CYP3A4 P08684 1/20 0.45
ESR2 Q92731 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
LTB4R2 Q9NPC1 2/20 0.44
HTT P42858 1/20 0.42
TP53 P04637 1/20 0.42
ESRRG P62508 3/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
ESRRB O95718 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18840276 0.85 ALDH1A1 (0.67) ALDH1A1GLATSHRESR1CYP3A4
SCHEMBL28091167 0.84 ESR1 (0.46) ALDH1A1GLATSHRESR1ESR2
SCHEMBL10926482 0.83 ALDH1A1 (0.48) ALDH1A1GLATSHRESR1CYP3A4
SCHEMBL5702191 0.83 ALDH1A1 (0.53) ALDH1A1GLATSHRCYP3A4MEN1
SCHEMBL6421500 0.83 ALDH1A1 (0.48) ALDH1A1GLATSHRESR1CYP3A4
SCHEMBL380050 0.83 ALDH1A1 (0.76) ALDH1A1GLATSHRCYP3A4MEN1
SCHEMBL250872 0.82 ALDH1A1 (0.52) ALDH1A1GLATSHRCYP3A4MEN1
SCHEMBL7575874 0.82 ALDH1A1 (0.47) ALDH1A1GLATSHRESR1CYP3A4
SCHEMBL11084579 0.82 ALDH1A1 (0.52) ALDH1A1GLATSHRCYP3A4MEN1
SCHEMBL915703 0.82 ALDH1A1 (0.52) ALDH1A1GLATSHRCYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673337-A2 ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS Sanofi-Aventis (FR) 2006-06-28 EP claimed
WO-2005033066-A2 ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2005-04-14 WO claimed
CN-102574855-A Pteridines and their use as pesticides DOW AGROSCIENCES LLC 2012-07-11 CN disclosed
EP-1673337-A2 ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS Sanofi-Aventis (FR) 2006-06-28 EP disclosed
WO-2005033066-A2 ARYLALKYLCARBAMATE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2005-04-14 WO disclosed
EP-1115712-A1 OXAZOLE COMPOUNDS AS PROSTAGLANDIN E2 AGONISTS OR ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-07-18 EP disclosed
WO-2000018744-A1 OXAZOLE COMPOUNDS AS PROSTAGLANDIN E2 AGONISTS OR ANTAGONISTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-04-06 WO disclosed
CN-1159797-A Aryloxy and arylthiopropanolamine derivative suseful as beta 3-adrenoreceptor agonists and antagonists of the beta 1 and beta 2-adrenoreceptors and pharmaceutical composition thereof SMITHKLINE BEECHAM PLC (GB) 1997-09-17 CN disclosed
EP-0772585-A1 ARYLOXY AND ARYLTHIOPROPANOLAMINE DERIVATIVES USEFUL AS BETA 3-ADRENORECEPTOR AGONISTS AND ANTAGONISTS OF THE BETA 1 AND BETA 2-ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF SMITHKLINE BEECHAM PLC (GB) 1997-05-14 EP disclosed
WO-1996004233-A1 ARYLOXY AND ARYLTHIOPROPANOLAMINE DERIVATIVES USEFUL AS BETA 3-ADRENORECEPTOR AGONISTS AND ANTAGONISTS OF THE BETA 1 AND BETA 2-ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF SMITHKLINE BEECHAM PLC (GB) 1996-02-15 WO disclosed
EP-0247476-B1 HYDROXYPHENYL URETHANES, PROCESS FOR THEIR MANUFACTURE, THEIR USES AND CHLOROFORMATES COMPRISING HYDROXYPHENYL URETHANE GROUPS BAYER AG (DE) 1990-12-27 EP disclosed
EP-0247483-A2 Process for the preparation of hydroxyphenyl urethanes BAYER AG (DE) 1987-12-02 EP disclosed
EP-0247476-A1 Hydroxyphenyl urethanes, process for their manufacture, their uses and chloroformates comprising hydroxyphenyl urethane groups BAYER AG (DE) 1987-12-02 EP disclosed