Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701915 | 0.82 | CYP3A4 (0.51) | CYP3A4SLC7A5HRH2 | |
| SCHEMBL27951220 | 0.78 | CYP3A4 (0.67) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Histidine SCHEMBL27702202 | 0.76 | CYP3A4 (0.78) | CYP3A4SLC7A5 | |
| SCHEMBL7420000 | 0.76 | SLC1A3 (0.36) | ALDH1A1MEN1KMT2ACA1CA2 | |
| SCHEMBL18162806 | 0.73 | CYP3A4 (0.73) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| SCHEMBL7962292 | 0.73 | CYP3A4 (0.73) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Histidine SCHEMBL503858 | 0.73 | CYP3A4 (0.88) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Histidine SCHEMBL30535770 | 0.72 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Histidine SCHEMBL28403793 | 0.72 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 | |
| Histidine SCHEMBL30039286 | 0.72 | CYP3A4 (0.71) | CYP3A4SLC7A5HRH4HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122628-B2 | Process for the synthesis of a peptide having a Trp residue | IPSEN MANUFACTURING IRELAND, LIMITED (IE) | 2006-10-17 | — | — | US | disclosed |
| EP-1343808-B1 | PROCESS FOR THE SYNTHESIS OF AN LHRH PEPTIDE | IPSEN MFG IRELAND LTD (IE) | 2006-09-13 | — | — | EP | disclosed |
| US-20040077827-A1 | Process for the synthesis of a peptide having a trp residue | IPSEN MANUFACTURING IRELAND LIMITED (IE) | 2004-04-22 | — | — | US | disclosed |
| EP-1343808-A2 | PROCESS FOR THE SYNTHESIS OF A PEPTIDE HAVING A TRP RESIDUE | Kinerton Limited (IE) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002051861-A2 | PROCESS FOR THE SYNTHESIS OF A PEPTIDE HAVING A TRYPTOPHAN RESIDUE | KINERTON LIMITED (IE) | 2002-07-04 | — | — | WO | disclosed |