Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570245 | 0.87 | NPC1 (0.45) | NPC1RAB9AHPGDKMT2AMAPT | |
| Toluic Acid SCHEMBL29018017 | 0.83 | KDM4E (0.47) | HPGDKMT2ALMNAALDH1A1HTT | |
| SCHEMBL127127 | 0.82 | NPC1 (0.53) | NPC1RAB9AHPGDKMT2AMAPT | |
| Toluic Acid SCHEMBL30367395 | 0.82 | AKR1C3 (0.49) | NPC1RAB9AHPGDKMT2ALMNA | |
| SCHEMBL570344 | 0.81 | NPC1 (0.46) | NPC1RAB9AHPGDKMT2AMAPT | |
| Toluic Acid SCHEMBL2528475 | 0.79 | ALDH1A1 (0.52) | NPC1RAB9AHPGDKMT2AMAPT | |
| Toluic Acid SCHEMBL29018276 | 0.79 | SMN1; SMN2 (0.45) | NPC1RAB9AHPGDKMT2AMAPT | |
| Toluic Acid SCHEMBL30367316 | 0.79 | SMN1; SMN2 (0.45) | NPC1RAB9AHPGDKMT2AMAPT | |
| SCHEMBL6006322 | 0.78 | NPC1 (0.46) | NPC1RAB9AHPGDKMT2AMAPT | |
| SCHEMBL5510171 | 0.77 | TSHR (0.50) | NPC1RAB9AHPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220056488-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | GENOMATICA INC (US) | 2022-02-24 | — | — | US | disclosed |
| WO-2012018624-A2 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | GENOMATICA, INC. (US) | 2012-02-09 | — | — | WO | disclosed |