Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570247 | 0.87 | NPC1 (0.44) | NPC1RAB9AHPGDPLK1PLK2 | |
| SCHEMBL127127 | 0.84 | NPC1 (0.53) | NPC1RAB9AHPGDPLK1PLK2 | |
| Toluic Acid SCHEMBL2528475 | 0.81 | ALDH1A1 (0.52) | NPC1RAB9AHPGDKMT2AMAPT | |
| SCHEMBL5510171 | 0.79 | TSHR (0.50) | NPC1RAB9AHPGDPLK1PLK2 | |
| SCHEMBL7628642 | 0.77 | NPC1 (0.47) | NPC1RAB9AHPGDPLK1PLK2 | |
| SCHEMBL7629352 | 0.77 | NPC1 (0.47) | NPC1RAB9AHPGDPLK1PLK2 | |
| SCHEMBL13355960 | 0.77 | NPC1 (0.47) | NPC1RAB9AHPGDPLK1PLK2 | |
| SCHEMBL30292582 | 0.76 | NPC1 (0.47) | NPC1RAB9AHPGDKMT2AMAPT | |
| SCHEMBL28158096 | 0.76 | NPC1 (0.44) | NPC1RAB9AHPGDPLK1PLK2 | |
| SCHEMBL29436920 | 0.76 | NPC1 (0.53) | NPC1RAB9AHPGDPLK1PLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018624-A2 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE | GENOMATICA, INC. (US) | 2012-02-09 | — | — | WO | disclosed |