Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1674130 | 0.82 | TSHR (0.70) | ALOX15TSHRALOX12HIF1ACYP3A4 | |
| SCHEMBL20762298 | 0.81 | ALOX15 (0.83) | ALOX15TSHRALOX12HIF1ACYP3A4 | |
| SCHEMBL18647 | 0.81 | TSHR (1.00) | ALOX15TSHRALOX12HIF1ACYP3A4 | |
| SCHEMBL5173922 | 0.81 | TSHR (1.00) | ALOX15TSHRALOX12HIF1ACYP3A4 | |
| SCHEMBL9006028 | 0.78 | ALOX15 (0.76) | ALOX15TSHRALOX12HIF1ACYP3A4 | |
| SCHEMBL1068524 | 0.76 | TSHR (0.72) | ALOX15TSHRALOX12HIF1ACYP3A4 | |
| SCHEMBL26215281 | 0.76 | ALOX15 (0.59) | ALOX15TSHRALOX12HIF1ACYP3A4 | |
| SCHEMBL11567514 | 0.75 | ALOX15 (0.86) | ALOX15TSHRALOX12HIF1ACYP3A4 | |
| SCHEMBL28146778 | 0.74 | TSHR (0.58) | ALOX15TSHRALOX12HIF1ACYP3A4 | |
| 1,2-Dibromoethane SCHEMBL4910588 | 0.74 | TSHR (0.83) | ALOX15TSHRALOX12HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689800-A1 | FLAME RETARDANT RADIATION CURABLE COMPOSITIONS | DSM IP Assets B.V. (NL) | 2006-08-16 | — | — | EP | disclosed |
| US-20050209357-A1 | Flame retardant radiation curable compositions | DSM IP ASSETS B.V. (NL) | 2005-09-22 | — | — | US | disclosed |
| WO-2005054330-A1 | FLAME RETARDANT RADIATION CURABLE COMPOSITIONS | DSM IP ASSETS B.V. (NL) | 2005-06-16 | — | — | WO | disclosed |