Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3413337 | 0.96 | THRB (0.45) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL10604787 | 0.88 | TSHR (0.46) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL11168121 | 0.84 | THRB (0.44) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL11175137 | 0.84 | THRB (0.42) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL7062178 | 0.84 | TSHR (0.40) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL9579758 | 0.83 | THRB (0.41) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL5292693 | 0.82 | THRB (0.41) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL7218047 | 0.82 | THRB (0.51) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL672151 | 0.82 | ALDH1A1 (0.43) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL22654587 | 0.81 | THRB (0.50) | THRBPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689800-A1 | FLAME RETARDANT RADIATION CURABLE COMPOSITIONS | DSM IP Assets B.V. (NL) | 2006-08-16 | — | — | EP | disclosed |
| US-20050209357-A1 | Flame retardant radiation curable compositions | DSM IP ASSETS B.V. (NL) | 2005-09-22 | — | — | US | disclosed |
| WO-2005054330-A1 | FLAME RETARDANT RADIATION CURABLE COMPOSITIONS | DSM IP ASSETS B.V. (NL) | 2005-06-16 | — | — | WO | disclosed |