SCHEMBL5704253

SCHEMBL5704253

COC(=O)c1cccc(OC(=O)Oc2ccccc2)c1C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.48
KDM4E B2RXH2 4/20 0.47
HSD17B10 Q99714 4/20 0.47
HPGD P15428 3/20 0.47
MAPT P10636 5/20 0.46
NPSR1 Q6W5P4 1/20 0.46
ALDH1A1 P00352 4/20 0.41
CYP1A2 P05177 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ELANE P08246 1/20 0.41
PRTN3 P24158 1/20 0.41
TSHR P16473 3/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 2/20 0.40
GLA P06280 1/20 0.40
ATM Q13315 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1282392 0.84 SLC6A3 (0.66) SLC6A3KDM4EHSD17B10HPGDMAPT
SCHEMBL7059062 0.82 SLC6A3 (0.51) SLC6A3KDM4EHSD17B10HPGDMAPT
SCHEMBL5706134 0.81 SLC6A3 (0.51) SLC6A3KDM4EHSD17B10HPGDMAPT
SCHEMBL247541 0.80 ATM (0.46) KDM4EHSD17B10HPGDMAPTNPSR1
SCHEMBL5706095 0.80 MAPT (0.68) SLC6A3KDM4EHSD17B10HPGDMAPT
SCHEMBL10222507 0.79 MAPT (0.50) SLC6A3KDM4EHSD17B10HPGDMAPT
SCHEMBL5706122 0.77 MAPT (0.54) SLC6A3KDM4EHSD17B10HPGDMAPT
SCHEMBL5700663 0.77 MAPT (0.51) SLC6A3KDM4EHSD17B10HPGDMAPT
SCHEMBL27437763 0.77 TSHR (0.53) SLC6A3KDM4EHSD17B10MAPTNPSR1
SCHEMBL5705960 0.77 SLC6A3 (0.52) SLC6A3KDM4EHSD17B10HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0575810-B2 Process for producing polycarbonate IDEMITSU KOSAN CO (JP) 2006-09-13 EP disclosed
EP-0646613-B1 A branched polycarbonate and a process for producing the same IDEMITSU PETROCHEMICAL CO (JP) 2002-02-27 EP disclosed
EP-0575810-B1 Process for producing polycarbonate IDEMITSU PETROCHEMICAL CO (JP) 1998-08-19 EP disclosed
EP-0360578-B1 Process for the production of polycarbonates GE PLASTICS JAPAN LTD (JP) 1998-08-05 EP disclosed
US-5625027-A Branched polycarbonate IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1997-04-29 US disclosed
US-5473046-A Interfacial polymerization; heat resistance, corrosion resistance IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-12-05 US disclosed
EP-0646613-A2 A branched polycarbonate and a process for producing the same IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1995-04-05 EP disclosed
US-5349043-A Transparent, heat resistant, water proof IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-09-20 US disclosed
US-5276129-A Aromatic polycarbonates with excellent color tone, heat resistance and water resistance GE PLASTICS JAPAN, LTD. (JP) 1994-01-04 US disclosed
EP-0575810-A2 Polycarbonate and process for producing the same IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1993-12-29 EP disclosed
US-5151491-A Nitrogen compound, a boric acid compound and a dihydroxy compound terminated with a monoalcohol GE PLASTICS JAPAN, LTD. (JP) 1992-09-29 US disclosed
EP-0360578-A2 Process for the production of polycarbonates GE PLASTICS JAPAN LTD. (JP) 1990-03-28 EP disclosed