SCHEMBL5705960

SCHEMBL5705960

COC(=O)c1ccccc1OC(=O)Oc1ccc(OC(C)(C)C)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 2/20 0.52
MAPT P10636 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50
HPGD P15428 3/20 0.48
KDM4E B2RXH2 2/20 0.48
HSD17B10 Q99714 1/20 0.48
KMT2A Q03164 4/20 0.47
HTT P42858 1/20 0.47
ALDH1A1 P00352 2/20 0.45
CYP1A2 P05177 1/20 0.45
MEN1 O00255 1/20 0.44
ELANE P08246 1/20 0.44
PRTN3 P24158 1/20 0.44
XBP1 P17861 1/20 0.44
PRSS1 P07477 1/20 0.43
ACR P10323 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ATM Q13315 1/20 0.41
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5705991 0.87 SLC6A3 (0.51) SLC6A3MAPTNPSR1HPGDKDM4E
SCHEMBL5706082 0.86 SLC6A3 (0.68) SLC6A3MAPTNPSR1KMT2AHTT
SCHEMBL5706095 0.86 MAPT (0.68) SLC6A3MAPTNPSR1HPGDKDM4E
SCHEMBL5706035 0.85 SLC6A3 (0.58) SLC6A3MAPTNPSR1HPGDKDM4E
SCHEMBL6812182 0.85 TSHR (0.50) MAPTNPSR1HPGDKDM4EHSD17B10
SCHEMBL1282392 0.85 SLC6A3 (0.66) SLC6A3MAPTHPGDKDM4EHSD17B10
SCHEMBL4384563 0.84 SLC6A3 (0.56) SLC6A3MAPTNPSR1HPGDKDM4E
SCHEMBL5706124 0.84 SLC6A3 (0.65) SLC6A3MAPTHPGDKDM4EHSD17B10
SCHEMBL5694595 0.84 SLC6A3 (0.56) SLC6A3MAPTNPSR1HPGDKDM4E
SCHEMBL5706122 0.84 MAPT (0.54) SLC6A3MAPTNPSR1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412411-B1 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GEN ELECTRIC (US) 2006-08-09 EP disclosed
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed