SCHEMBL5704646

SCHEMBL5704646

C=C(CC(=O)O)C(=O)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15153790 1.00 THRB (0.39) THRBALOX15HSD17B10TET2
SCHEMBL15153736 0.87 ALOX15 (0.31) ALOX15HSD17B10
SCHEMBL942320 0.86 THRB (0.31) THRB
SCHEMBL8640185 0.83 THRB (0.37) THRBALOX15HSD17B10
SCHEMBL9718613 0.81 THRB (0.36) THRB
SCHEMBL9718576 0.81 THRB (0.36) THRB
SCHEMBL9718579 0.81 THRB (0.36) THRB
SCHEMBL9718557 0.81 THRB (0.36) THRB
SCHEMBL2321792 0.81 THRB (0.36) THRB
SCHEMBL758044 0.81 THRB (0.36) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11186731-B2 Slippery self-lubricating polymer surfaces PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-11-30 US claimed
US-20180327608-A1 SLIPPERY SELF-LUBRICATING POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2018-11-15 US claimed
US-20170174928-A1 Superhydrophobic and Oleophobic Ceramic Polymer Composite Coating UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2017-06-22 US claimed
WO-2016014952-A1 SUPERHYDROPHOBIC AND OLEOPHOBIC CERAMIC POLYMER COMPOSITE COATING UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2016-01-28 WO claimed
US-6870662-B2 Methods of surface modification for improving electrophoretic display performance SIPIX IMAGING, INC. (US) 2005-03-22 US claimed
WO-2003102685-A9 METHODS OF SURFACE MODIFICATION FOR IMPROVING ELECTROPHORETIC DISLAY PERFORMANCE SIPIX IMAGING INC (US) 2004-02-19 WO claimed
WO-2003102685-A2 METHODS OF SURFACE MODIFICATION FOR IMPROVING ELECTROPHORETIC DISLAY PERFORMANCE SIPIX IMAGING, INC. (US) 2003-12-11 WO claimed
US-20030210455-A1 Methods of surface modification for improving electrophoretic display performance E INK CALIFORNIA, LLC 2003-11-13 US claimed
CN-1455663-A Novel aerosol formulation containing polar fluorinated molecule ASTRAZENECA AB (SE) 2003-11-12 CN claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
WO-2025043220-A1 FLUID CONDUITS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-02-27 WO disclosed
WO-2024086390-A9 CONTROLLABLE SLIPPERY POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-07-18 WO disclosed
EP-2872572-B1 SLIPPERY SELF-LUBRICATING POLYMER SURFACES HARVARD COLLEGE (US) 2024-06-19 EP disclosed
WO-2024086390-A2 CONTROLLABLE SLIPPERY POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-04-25 WO disclosed
EP-0219312-B1 Improved fluorine containing polymeric compositions useful in contact lenses POLYMER TECHNOLOGY CORP (US) 1995-12-20 EP disclosed
US-4996275-A With silicon group-substituted addition polymers; oxygen permeability, hydrophilic, deposit resistance POLYMER TECHNOLOGY CORPORATION (US) 1991-02-26 US disclosed
US-4686267-A Fluorine containing polymeric compositions useful in contact lenses POLYMER TECHNOLOGY CORPORATION (US) 1987-08-11 US disclosed
EP-0219312-A2 Improved fluorine containing polymeric compositions useful in contact lenses POLYMER TECHNOLOGY CORPORATION (US) 1987-04-22 EP disclosed