SCHEMBL5704689

SCHEMBL5704689

COC(=O)C(F)(OC(F)(F)C(F)(OC(F)(F)C(F)(OC(F)(F)C(F)(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)F)C(F)(F)F)C(F)(F)F)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1218499 1.00 ALDH1A1 (0.36) ALDH1A1
SCHEMBL5693985 1.00 ALDH1A1 (0.36) ALDH1A1
SCHEMBL197030 0.91 ALDH1A1 (0.41) ALDH1A1
SCHEMBL29083169 0.89 ALDH1A1 (0.31) ALDH1A1
SCHEMBL500083 0.88 ALDH1A1 (0.31) ALDH1A1
SCHEMBL15357312 0.86 ALDH1A1 (0.30) ALDH1A1
SCHEMBL22142556 0.86 ALDH1A1 (0.35) ALDH1A1
SCHEMBL594846 0.86 ALDH1A1 (0.35) ALDH1A1
SCHEMBL22118489 0.86 ALDH1A1 (0.35) ALDH1A1
SCHEMBL22118505 0.86 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1303258-B1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2006-10-11 EP claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
US-9971306-B2 Coating of surfaces intended for horology by using catanionic compositions containing phosphonic molecules and amines ASSOCIATION SUISSE POUR LA RECHERCHE HORLOGÈRE (CH) 2018-05-15 US disclosed
US-20150103639-A1 COATING OF SURFACES INTENDED FOR HOROLOGY BY USING CATANIONIC COMPOSITIONS CONTAINING PHOSPHONIC MOLECULES AND AMINES ASSOCIATION SUISSE POUR LA RECHERCHE HORLOGERE (CH) 2015-04-16 US disclosed
EP-1303258-B1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2006-10-11 EP disclosed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US disclosed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP disclosed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO disclosed