Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | ODC1 | P11926 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188179 | 1.00 | GRM2 (0.41) | GRM2GRM3SLC7A5ARG1ARG2 | |
| SCHEMBL188178 | 1.00 | GRM2 (0.41) | GRM2GRM3SLC7A5ARG1ARG2 | |
| SCHEMBL4314004 | 0.77 | GRM2 (0.43) | GRM2GRM3SLC7A5ARG1ARG2 | |
| SCHEMBL1629778 | 0.75 | MEN1 (0.40) | GRM2GRM3ARG1ARG2ODC1 | |
| SCHEMBL11208132 | 0.74 | GABRP (0.42) | ARG1ARG2ODC1 | |
| SCHEMBL10021004 | 0.72 | GRM2 (0.37) | GRM2GRM3SLC7A5CYP2D6 | |
| SCHEMBL21821202 | 0.72 | GRM2 (0.46) | GRM2GRM3SLC7A5ARG1ARG2 | |
| SCHEMBL497762 | 0.72 | GRM2 (0.46) | GRM2GRM3SLC7A5ARG1ARG2 | |
| SCHEMBL21199502 | 0.71 | MEN1 (0.38) | ARG1ARG2ODC1CYP1A2 | |
| SCHEMBL5704692 | 0.71 | MEN1 (0.38) | ARG1ARG2ODC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030194378-A1 | Novel aerosol formulation containing a polar fluorinated molecule | ASTRAZENECA AB (SE) | 2003-10-16 | — | — | US | claimed |
| EP-1303258-A1 | NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE | AstraZeneca AB (SE) | 2003-04-23 | — | — | EP | claimed |
| WO-2002003958-A1 | NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE | ASTRAZENECA AB (SE) | 2002-01-17 | — | — | WO | claimed |
| EP-1303258-B1 | NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE | ASTRAZENECA AB (SE) | 2006-10-11 | — | — | EP | disclosed |
| US-20030194378-A1 | Novel aerosol formulation containing a polar fluorinated molecule | ASTRAZENECA AB (SE) | 2003-10-16 | — | — | US | disclosed |
| EP-1303258-A1 | NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE | AstraZeneca AB (SE) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002003958-A1 | NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE | ASTRAZENECA AB (SE) | 2002-01-17 | — | — | WO | disclosed |