Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.63 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5704787 | 0.99 | HTR6 (0.62) | HTR6TDO2 | |
| Hydrochloric Acid SCHEMBL6376332 | 0.82 | HTR6 (0.58) | HTR6 | |
| SCHEMBL5704918 | 0.81 | HTR6 (0.60) | HTR6 | |
| Hydrochloric Acid SCHEMBL5704989 | 0.80 | HTR6 (0.59) | HTR6 | |
| SCHEMBL5704880 | 0.79 | HTR6 (0.81) | HTR6 | |
| SCHEMBL5704720 | 0.79 | HTR6 (0.82) | HTR6 | |
| Hydrochloric Acid SCHEMBL5704887 | 0.79 | HTR6 (0.79) | HTR6 | |
| Hydrochloric Acid SCHEMBL5705061 | 0.78 | HTR6 (0.80) | HTR6 | |
| SCHEMBL5704909 | 0.78 | HTR6 (0.78) | HTR6 | |
| SCHEMBL5704872 | 0.78 | HTR6 (1.00) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335722-B1 | INDOLYL-SULFONYL- COMPOUNDS USEFUL IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 2006-08-30 | — | — | EP | claimed |