Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.65 |
| ▸ | STS | P08842 | 3/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704771 | 0.92 | HTR6 (0.67) | HTR6STSGPR119 | |
| SCHEMBL7142308 | 0.86 | HTR6 (0.72) | HTR6 | |
| SCHEMBL6375028 | 0.86 | HTR6 (0.70) | HTR6STS | |
| SCHEMBL5704817 | 0.84 | HTR6 (0.64) | HTR6STS | |
| SCHEMBL5704927 | 0.81 | HTR6 (0.60) | HTR6STS | |
| SCHEMBL5704981 | 0.80 | HTR6 (0.66) | HTR6STSGPR119 | |
| SCHEMBL5698323 | 0.80 | HTR6 (0.54) | HTR6GPR119 | |
| SCHEMBL5705003 | 0.80 | HTR6 (0.53) | HTR6STSGPR119 | |
| SCHEMBL5704975 | 0.79 | HTR6 (1.00) | HTR6 | |
| SCHEMBL5704869 | 0.79 | HTR6 (0.66) | HTR6STSGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335722-B1 | INDOLYL-SULFONYL- COMPOUNDS USEFUL IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 2006-08-30 | — | — | EP | disclosed |
| US-20050176705-A1 | Compounds useful in the treatment of cns disorders | SMITHKLINE BEECHAM P.L.C. (GB) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176705-A1 | Compounds useful in the treatment of cns disorders | SLC18A2, CNR2, TPH2 | HTR6 22/4885STS 3088/4885GPR119 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.