Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.36 |
| ▸ | RXRG | P48443 | 7/20 | 0.36 |
| ▸ | RXRB | P28702 | 7/20 | 0.36 |
| ▸ | RARA | P10276 | 6/20 | 0.36 |
| ▸ | RARB | P10826 | 8/20 | 0.35 |
| ▸ | RARG | P13631 | 7/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.35 |
| ▸ | CYP26B1 | Q9NR63 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061673 | 0.83 | RXRA (0.39) | RXRARXRGRXRBRARARARB | |
| SCHEMBL8809982 | 0.81 | HIF1A (0.41) | RXRARXRGRXRBRARARARB | |
| SCHEMBL8810467 | 0.72 | CDC25B (0.41) | RXRARXRGRXRBRARARARB | |
| SCHEMBL8310387 | 0.72 | RXRA (0.36) | RXRARXRGRXRBRARARARB | |
| SCHEMBL5009416 | 0.72 | RXRA (0.41) | RXRARXRGRXRBRARARARB | |
| SCHEMBL29401105 | 0.72 | RXRA (0.41) | RXRARXRGRXRBRARARARB | |
| SCHEMBL15665861 | 0.71 | RXRA (0.41) | RXRARXRGRXRBRARARARB | |
| SCHEMBL7624438 | 0.71 | PBRM1 (0.44) | RXRARXRGRXRBRARARARB | |
| Lithium SCHEMBL29602414 | 0.70 | RXRA (0.40) | RXRARXRGRXRBRARARARB | |
| SCHEMBL11599145 | 0.69 | RXRA (0.42) | RXRARXRGRXRBRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294945-B1 | METHOD FOR DETECTING CYTOSINE METHYLATIONS | EPIGENOMICS AG (DE) | 2006-08-30 | — | — | EP | claimed |