Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 8/20 | 0.42 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 6/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635782 | 0.87 | CAPN1 (0.36) | CAPN1CNR2CNR1POLBSMN1; SMN2 | |
| SCHEMBL4622515 | 0.80 | CAPN1 (0.46) | CAPN1CAPNS1 | |
| SCHEMBL3588905 | 0.77 | CAPN1 (0.44) | CAPN1 | |
| SCHEMBL3588879 | 0.77 | CAPN1 (0.47) | CAPN1CAPNS1 | |
| SCHEMBL27428208 | 0.76 | CAPN1 (0.57) | CAPN1CAPNS1 | |
| SCHEMBL7515309 | 0.76 | CAPN1 (0.57) | CAPN1CAPNS1 | |
| SCHEMBL27428206 | 0.76 | CAPN1 (0.57) | CAPN1CAPNS1 | |
| SCHEMBL3583085 | 0.73 | CASP1 (0.42) | CAPN1CAPNS1 | |
| SCHEMBL3579899 | 0.73 | CASP1 (0.42) | CAPN1CAPNS1 | |
| SCHEMBL8812311 | 0.72 | CAPN1 (0.51) | CAPN1CAPNS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701974-A2 | NOVEL 2-HYDROXYTETRAHYDROFURANE DERIVATIVES AND USE THEREOF AS MEDICAMENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005056551-A2 | NOVEL 2-HYDROXYTETRAHYDROFURANE DERIVATIVES AND USE THEREOF AS MEDICAMENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2005-06-23 | — | — | WO | disclosed |