Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.42 |
| ▸ | CASP3 | P42574 | 4/20 | 0.42 |
| ▸ | CASP6 | P55212 | 3/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3583085 | 1.00 | CASP1 (0.42) | CASP1CASP3CASP6CASP8CASP7 | |
| SCHEMBL3588905 | 0.88 | CAPN1 (0.44) | CASP1CASP3CASP6CASP8CASP7 | |
| SCHEMBL3579903 | 0.84 | CASP1 (0.44) | CASP1CASP3CASP6CASP8CASP7 | |
| SCHEMBL4540395 | 0.76 | CAPN1 (0.56) | CAPN1CAPNS1 | |
| SCHEMBL3588992 | 0.76 | CASP1 (0.46) | CASP1CASP3CASP6CASP8CASP7 | |
| SCHEMBL3635782 | 0.74 | CAPN1 (0.36) | CAPN1 | |
| SCHEMBL5705355 | 0.73 | CAPN1 (0.42) | CAPN1CAPNS1 | |
| SCHEMBL3588908 | 0.72 | CAPN1 (0.46) | CASP1CASP3CASP6CASP8CASP7 | |
| SCHEMBL3582023 | 0.72 | CAPN1 (0.66) | CASP1CASP3CASP6CASP8CAPN1 | |
| Iodide SCHEMBL3589792 | 0.71 | CAPN1 (0.65) | CASP1CASP3CASP6CASP8CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659266-B2 | Amidine derivatives and their applications as a medicament | S.C.R.A.S. (FR) | 2010-02-09 | — | — | US | disclosed |
| US-20090018120-A1 | AMIDINE DERIVATIVES AND THEIR APPLICATIONS AS A MEDICAMENT | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018120-A1 | AMIDINE DERIVATIVES AND THEIR APPLICATIONS AS A MEDICAMENT | CAPN2, CAPN9, CAPN1 | CASP1 458/4885CASP3 246/4885CASP6 534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.