Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | CTSH | P09668 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 7/20 | 0.34 |
| ▸ | CTSS | P25774 | 4/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635782 | 0.81 | CAPN1 (0.36) | CNR1CNR2 | |
| SCHEMBL4620561 | 0.78 | AAK1 (0.38) | CTSLCTSBCTSHCTSKCPB2 | |
| SCHEMBL4689653 | 0.77 | CPB2 (0.39) | CTSKCTSSCPB2 | |
| SCHEMBL5705288 | 0.76 | KDM1A (0.39) | — | |
| SCHEMBL4807064 | 0.73 | CAPN1 (0.31) | — | |
| SCHEMBL3617417 | 0.70 | CTSK (0.42) | CTSLCTSBCTSHCTSKCTSS | |
| SCHEMBL13710937 | 0.70 | CTSK (0.42) | CTSLCTSBCTSHCTSKCTSS | |
| SCHEMBL13711061 | 0.70 | CTSK (0.42) | CTSLCTSBCTSHCTSKCTSS | |
| SCHEMBL18435239 | 0.69 | CTSK (0.44) | CTSLCTSBCTSHCTSKCPB2 | |
| SCHEMBL13707910 | 0.69 | CTSK (0.44) | CTSLCTSBCTSHCTSKCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701974-A2 | NOVEL 2-HYDROXYTETRAHYDROFURANE DERIVATIVES AND USE THEREOF AS MEDICAMENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005056551-A2 | NOVEL 2-HYDROXYTETRAHYDROFURANE DERIVATIVES AND USE THEREOF AS MEDICAMENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2005-06-23 | — | — | WO | disclosed |