SCHEMBL5705600

SCHEMBL5705600

C/C(CC(C)C)=N\NC(=O)c1c(O)cccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 1/20 0.54
▸ TAS1R3 Q7RTX0 1/20 0.47
▸ TAS1R1 Q7RTX1 1/20 0.47
▸ TAS1R2 Q8TE23 1/20 0.47
▸ SMN1; SMN2 Q16637 4/20 0.47
▸ GAA P10253 4/20 0.47
▸ KDM4E B2RXH2 4/20 0.42
▸ THRB P10828 2/20 0.42
▸ MAPT P10636 2/20 0.42
▸ TDP1 Q9NUW8 2/20 0.42
▸ CA12 O43570 2/20 0.40
▸ CA1 P00915 2/20 0.40
▸ CA2 P00918 2/20 0.40
▸ CA7 P43166 2/20 0.40
▸ CA9 Q16790 2/20 0.40
▸ CA14 Q9ULX7 2/20 0.40
▸ PPIA P62937 1/20 0.39
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5705602 1.00 RAB9A (0.54) RAB9ATAS1R3TAS1R1TAS1R2SMN1; SMN2
SCHEMBL21433611 0.85 GAA (0.55) RAB9ASMN1; SMN2GAAKDM4ETHRB
SCHEMBL21433610 0.85 GAA (0.55) RAB9ASMN1; SMN2GAAKDM4ETHRB
SCHEMBL23202438 0.85 RAB9A (0.47) RAB9ASMN1; SMN2GAAMEN1KMT2A
SCHEMBL23222462 0.85 RAB9A (0.47) RAB9ASMN1; SMN2GAAMEN1KMT2A
SCHEMBL23202623 0.84 RAB9A (0.46) RAB9ASMN1; SMN2GAAKDM4EMAPT
SCHEMBL5705557 0.84 GAA (0.68) RAB9ASMN1; SMN2GAAKDM4ETHRB
SCHEMBL23222464 0.84 RAB9A (0.46) RAB9ASMN1; SMN2GAAKDM4EMAPT
SCHEMBL30240785 0.84 GAA (0.68) RAB9ASMN1; SMN2GAAKDM4ETHRB
SCHEMBL1843216 0.84 GAA (0.68) RAB9ASMN1; SMN2GAAKDM4ETHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11306201-B2 Rubber composition for tires and tire BRIDGESTONE CORPORATION (JP) 2022-04-19 — — US disclosed
EP-3626773-B1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORP (JP) 2021-12-08 — — EP disclosed
EP-3805306-A1 RUBBER COMPOSITION AND TIRE Bridgestone Corporation (JP) 2021-04-14 — — EP disclosed
US-20200283613-A1 RUBBER COMPOSITION FOR TIRES AND TIRE BRIDGESTONE CORPORATION (JP) 2020-09-10 — — US disclosed
EP-3626773-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE Bridgestone Corporation (JP) 2020-03-25 — — EP disclosed
US-20200079933-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2020-03-12 — — US disclosed
EP-1420044-B1 Hydrazone derivatives OTSUKA CHEM HOLDINGS CO LTD (JP) 2006-09-06 — — EP disclosed
EP-0909788-B1 RUBBER COMPOSITION AND PNEUMATIC TIRES BRIDGESTONE CORP (JP) 2004-12-01 — — EP disclosed
EP-1420044-A2 Rubber composition and pneumatic tire Bridgestone Corporation (JP) 2004-05-19 — — EP disclosed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 — — US disclosed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 — — EP disclosed
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