Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FGB | P02675 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907880 | 0.84 | FYN (0.37) | SMN1; SMN2ALDH1A1KMT2AMEN1FGB | |
| SCHEMBL4899064 | 0.72 | KDM4E (0.55) | SMN1; SMN2ALDH1A1KMT2AMEN1FGB | |
| SCHEMBL5599264 | 0.71 | KDM4E (0.41) | SMN1; SMN2ALDH1A1KMT2AMEN1FGB | |
| SCHEMBL5600123 | 0.68 | MAPT (0.34) | SMN1; SMN2ALDH1A1KMT2ATSHRMAPT | |
| SCHEMBL4908334 | 0.66 | L3MBTL1 (0.45) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL501770 | 0.66 | L3MBTL1 (0.40) | SMN1; SMN2ALDH1A1KMT2AALOX15MAPK1 | |
| SCHEMBL4908743 | 0.63 | MAPT (0.51) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1TSHR | |
| SCHEMBL4899031 | 0.62 | L3MBTL1 (0.39) | L3MBTL1MAPTFFAR1KDM4E | |
| SCHEMBL4910626 | 0.62 | HRH3 (0.51) | SMN1; SMN2MAPK1L3MBTL1TSHRMAPT | |
| SCHEMBL4908660 | 0.61 | KDM4E (0.42) | SMN1; SMN2MAPK1L3MBTL1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695704-A1 | Derivatives of aryl (or heteroaryl) azolylcarbinols for the treatment of fibromyalgia | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-08-30 | — | — | EP | disclosed |