Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FGB | P02675 | 1/20 | 0.40 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4899064 | 0.82 | KDM4E (0.55) | KDM4EKMT2AALOX15HSD17B10MEN1 | |
| SCHEMBL5600881 | 0.78 | FFAR1 (0.53) | KDM4EFFAR1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL5599337 | 0.71 | KDM4E (0.49) | KDM4EKMT2AFFAR1L3MBTL1MAPT | |
| SCHEMBL5599443 | 0.71 | KDM4E (0.46) | KDM4EALOX15HSD17B10FFAR1L3MBTL1 | |
| SCHEMBL5705642 | 0.71 | SMN1; SMN2 (0.34) | KDM4EKMT2AALOX15HSD17B10MEN1 | |
| SCHEMBL4907880 | 0.71 | FYN (0.37) | KDM4EKMT2AALOX15HSD17B10MEN1 | |
| SCHEMBL4908743 | 0.69 | MAPT (0.51) | KMT2AL3MBTL1MAPTTSHRALDH1A1 | |
| SCHEMBL4057810 | 0.69 | KDM4E (0.50) | KDM4EKMT2AALOX15HSD17B10MEN1 | |
| SCHEMBL5599142 | 0.69 | FFAR1 (0.52) | KDM4EKMT2AALOX15HSD17B10MEN1 | |
| SCHEMBL4900554 | 0.68 | MAPT (0.49) | KMT2AL3MBTL1MAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1755678-A2 | ACTIVE SUBSTANCE COMBINATION OF A CARBINOL COMPOUND AND AN OPIOID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005097192-A2 | ACTIVE SUBSTANCE COMBINATION OF A CARBINOL COMPOUND AND AN OPIOID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-10-20 | — | — | WO | disclosed |