Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692954 | 0.86 | BCHE (0.36) | KDM4EALDH1A1 | |
| SCHEMBL4694471 | 0.84 | CYP1A2 (0.34) | KDM4EALDH1A1 | |
| SCHEMBL4694104 | 0.68 | SIGMAR1 (0.33) | — | |
| SCHEMBL4696483 | 0.68 | BCHE (0.31) | — | |
| SCHEMBL4695663 | 0.67 | CHRM2 (0.35) | NPY5RKDM4EALDH1A1 | |
| SCHEMBL4695791 | 0.67 | — | — | |
| SCHEMBL4693296 | 0.65 | CYP1A2 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL6231367 | 0.63 | NPY5R (0.40) | NPY5RKDM4EALDH1A1 | |
| SCHEMBL5234902 | 0.62 | PDE5A (0.42) | KDM4E | |
| Napazimone SCHEMBL30092410 | 0.59 | KDM4E (0.54) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1684749-A1 | USE OF 1,3-DIAZA-DIBENZO[e,h] AZULENES FOR THE MANUFACTURE OF PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS | PLIVA-ISTRAZIVACKI INSTITUT d.o.o. (HR) | 2006-08-02 | — | — | EP | claimed |
| WO-2005049016-A1 | USE OF 1,3-DIAZA-DIBENZO[e,h]AZULENES FOR THE MANUFACTURE OF PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS | PLIVA-ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2005-06-02 | — | — | WO | claimed |