Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | USP8 | P40818 | 1/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31092489 | 0.68 | KDM4E (0.55) | L3MBTL1ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL5225539 | 0.68 | CYP2A6 (0.40) | L3MBTL1ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL5244308 | 0.67 | NPY5R (0.59) | NPY5RL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL2293985 | 0.66 | NPY5R (0.40) | NPY5RL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL4692166 | 0.65 | ALDH1A1 (0.49) | NPY5RL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL4696051 | 0.64 | NPY5R (0.38) | NPY5RL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL19044532 | 0.61 | KDM4E (0.43) | NPY5RL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL38662232 | 0.61 | TGFBR1 (0.49) | NPY5RL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL5244989 | 0.60 | NPY5R (0.65) | NPY5RL3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL19537629 | 0.59 | ALDH1A1 (0.48) | NPY5RL3MBTL1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509528-A2 | 1,3-DIAZA-DIBENZOAZULENES AS INHIBITORS OF TUMOUR NECROSIS FACTOR PRODUCTION AND INTERMEDIATES FOR THE PREPARATION THEREOF | Pliva-Istrazivacki Institut D.D.O. (HR) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099823-A2 | 1,3-DIAZA-DIBENZOAZULENES AS INHIBITORS OF TUMOUR NECROSIS FACTOR PRODUCTION AND INTERMEDIATES FOR THE PREPARATION THEREOF | PLIVA - ISTRAZIVACKI INSTITUT D.O.O. (HR) | 2003-12-04 | — | — | WO | disclosed |