SCHEMBL5706124

SCHEMBL5706124

COC(=O)c1ccc(OC(=O)Oc2ccccc2C(=O)OC)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.65
KMT2A Q03164 6/20 0.58
ALDH1A1 P00352 2/20 0.58
MAPT P10636 3/20 0.56
PRSS1 P07477 1/20 0.56
ACR P10323 1/20 0.56
LMNA P02545 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
KDM4E B2RXH2 3/20 0.51
HPGD P15428 2/20 0.51
HSD17B10 Q99714 1/20 0.51
POLB P06746 2/20 0.50
HTT P42858 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
RAB9A P51151 1/20 0.49
TSHR P16473 1/20 0.49
MEN1 O00255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706035 0.89 SLC6A3 (0.58) SLC6A3KMT2AALDH1A1MAPTPRSS1
SCHEMBL5705969 0.89 SLC6A3 (0.56) SLC6A3KMT2AALDH1A1MAPTPRSS1
SCHEMBL5706133 0.89 SLC6A3 (0.52) SLC6A3KMT2AALDH1A1MAPTPRSS1
SCHEMBL1282392 0.89 SLC6A3 (0.66) SLC6A3KMT2AALDH1A1MAPTPRSS1
SCHEMBL5694595 0.88 SLC6A3 (0.56) SLC6A3KMT2AALDH1A1MAPTPRSS1
SCHEMBL4384563 0.88 SLC6A3 (0.56) SLC6A3KMT2AALDH1A1MAPTPRSS1
SCHEMBL47893 0.87 SLC6A3 (0.71) SLC6A3KMT2AALDH1A1MAPTPRSS1
SCHEMBL29551673 0.87 SLC6A3 (0.71) SLC6A3KMT2AALDH1A1MAPTPRSS1
SCHEMBL5706076 0.85 SLC6A3 (0.87) SLC6A3KMT2AALDH1A1MAPTPRSS1
SCHEMBL5705958 0.85 SLC6A3 (0.57) SLC6A3KMT2AALDH1A1MAPTPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1412411-B1 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GEN ELECTRIC (US) 2006-08-09 EP disclosed
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
EP-1412411-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-04-28 EP disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
WO-2003008481-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-01-30 WO disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed