Sugi Predict

Sugi Predict / Compounds / SCHEMBL4384563

SCHEMBL4384563

SCHEMBL4384563

COC(=O)c1ccccc1OC(=O)Oc1ccc(C)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC6A3 Q01959 1/20 0.56
▸ HPGD P15428 3/20 0.51
▸ KDM4E B2RXH2 2/20 0.51
▸ HSD17B10 Q99714 2/20 0.51
▸ CYP1A2 P05177 2/20 0.51
▸ CYP3A4 P08684 1/20 0.51
▸ CYP2C9 P11712 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ MAPT P10636 4/20 0.50
▸ KMT2A Q03164 4/20 0.50
▸ HTT P42858 2/20 0.50
▸ NPSR1 Q6W5P4 2/20 0.50
▸ XBP1 P17861 1/20 0.50
▸ HSP90AA1 P07900 1/20 0.48
▸ ALDH1A1 P00352 2/20 0.48
▸ PTK2B Q14289 1/20 0.48
▸ RXFP1 Q9HBX9 1/20 0.48
▸ PRSS1 P07477 1/20 0.46
▸ ACR P10323 1/20 0.46
▸ TSHR P16473 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5694595 1.00 SLC6A3 (0.56) SLC6A3HPGDKDM4EHSD17B10CYP1A2
SCHEMBL4394452 0.91 PTK2B (0.57) HPGDKDM4EHSD17B10CYP1A2CYP3A4
SCHEMBL5706035 0.89 SLC6A3 (0.58) SLC6A3HPGDKDM4EHSD17B10CYP1A2
SCHEMBL1282392 0.89 SLC6A3 (0.66) SLC6A3HPGDKDM4EHSD17B10CYP1A2
SCHEMBL13971012 0.88 PTK2B (0.55) HPGDKDM4EHSD17B10CYP1A2CYP3A4
SCHEMBL5706124 0.88 SLC6A3 (0.65) SLC6A3HPGDKDM4EHSD17B10CYP1A2
SCHEMBL4385356 0.88 HPGD (0.61) SLC6A3HPGDKDM4EHSD17B10CYP1A2
SCHEMBL4390471 0.88 PTK2B (0.55) HPGDKDM4EHSD17B10CYP1A2CYP3A4
SCHEMBL29551673 0.87 SLC6A3 (0.71) SLC6A3HPGDKDM4EHSD17B10CYP1A2
SCHEMBL47893 0.87 SLC6A3 (0.71) SLC6A3HPGDKDM4EHSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 — — EP disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 — — US disclosed
US-7425603-B2 Polymers, polymer compositions, and method of preparation GENERAL ELECTRIC COMPANY (US) 2008-09-16 — — US disclosed
US-7425603-B2 Polymers, polymer compositions, and method of preparation GENERAL ELECTRIC COMPANY (US) 2008-09-16 — — US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 — — US disclosed
US-7381786-B2 Methods of polymer preparation using polycyclic dihydroxy compounds GENERAL ELECTRIC COMPANY (US) 2008-06-03 — — US disclosed
US-7375177-B2 Polymers, polymer compositions and method of preparation GENERAL ELECTRIC COMPANY (US) 2008-05-20 — — US disclosed
US-7326763-B2 Polymers, polymer compositions and method of preparation GENERAL ELECTRIC COMPANY (US) 2008-02-05 — — US disclosed
US-20070260033-A1 METHODS OF POLYMER PREPARATION USING POLYCYCLIC DIHYDROXY COMPOUNDS GENERAL ELECTRIC COMPANY (US) 2007-11-08 — — US disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 — — EP disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 — — US disclosed
WO-2003008481-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-01-30 — — WO disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 — — US disclosed
US-6262210-B1 TRANSESTERIFYING DIALKYL CARBONATE, ALKYL ARYL CARBONATE OR MIXTURE WITH AROMATIC MONOHYDROXY COMPOUND IN PRESENCE OF METAL CONTAINING CATALYST TO OBTAIN HIGH BOILING POINT REACTION MIXTURE CONTAINING AROMATIC CARBONATE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-07-17 — — US disclosed
EP-1016648-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-07-05 — — EP disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 — — EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 — — EP disclosed
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 — — EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 — — US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 SLC6A3 839/4885HPGD 3545/4885KDM4E 481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.