Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | C1S | P09871 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621531 | 0.82 | CES1 (0.58) | CES1CES2AKR1B1PLAUMEN1 | |
| Phenylacetic Acid SCHEMBL27804643 | 0.80 | AKR1B1 (0.77) | CES1CES2AKR1B1PLAUHIF1A | |
| Bicarbonate SCHEMBL6989215 | 0.80 | CES1 (0.56) | CES1CES2AKR1B1PLAUHIF1A | |
| Phenylacetic Acid SCHEMBL28326941 | 0.78 | AKR1B1 (0.74) | CES1CES2AKR1B1PLAUHIF1A | |
| SCHEMBL4461405 | 0.77 | PRSS1 (0.61) | PLAUF2PLGPRSS1PRSS2 | |
| SCHEMBL5188950 | 0.77 | CES1 (0.73) | CES1CES2AKR1B1HIF1AMEN1 | |
| SCHEMBL10584878 | 0.77 | CES1 (0.58) | CES1CES2AKR1B1HIF1AMEN1 | |
| SCHEMBL10584888 | 0.77 | CES1 (0.58) | CES1CES2AKR1B1HIF1AMEN1 | |
| Acetic Acid SCHEMBL3665413 | 0.77 | CES1 (0.52) | CES1CES2AKR1B1PLAUHIF1A | |
| SCHEMBL25676 | 0.77 | CES1 (0.64) | CES1CES2AKR1B1HIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697309-B1 | BENZOYL-SUBSTITUTED PHENYLALANINE AMIDES | BASF SE (DE) | 2014-04-23 | — | — | EP | claimed |
| EP-1716120-A1 | HERBICIDAL HETEROAROYL-SUBSTITUTED PHENYLALANINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-02 | — | — | EP | claimed |
| EP-1697309-A2 | BENZOYL-SUBSTITUTED PHENYLALANINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-06 | — | — | EP | claimed |
| WO-2005061443-A2 | BENZOYL-SUBSTITUTED PHENYLALANINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-07 | — | — | WO | claimed |
| WO-2005061464-A1 | HERBICIDAL HETEROAROYL-SUBSTITUTED PHENYLALANINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-07 | — | — | WO | claimed |
| EP-2427451-B1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |
| EP-1697309-B1 | BENZOYL-SUBSTITUTED PHENYLALANINE AMIDES | BASF SE (DE) | 2014-04-23 | — | — | EP | disclosed |
| EP-1716120-A1 | HERBICIDAL HETEROAROYL-SUBSTITUTED PHENYLALANINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-02 | — | — | EP | disclosed |
| EP-1697309-A2 | BENZOYL-SUBSTITUTED PHENYLALANINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005061464-A1 | HERBICIDAL HETEROAROYL-SUBSTITUTED PHENYLALANINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005061443-A2 | BENZOYL-SUBSTITUTED PHENYLALANINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-07 | — | — | WO | disclosed |