Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.61 |
| ▸ | F10 | P00742 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 7/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | C1S | P09871 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118456 | 0.84 | PRSS1 (0.64) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL27392418 | 0.82 | PRSS1 (0.51) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL19990975 | 0.81 | PRSS1 (0.65) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL27595727 | 0.79 | PRSS1 (0.65) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL5706141 | 0.77 | CES1 (0.54) | PRSS1PRSS2PRSS3F2PLAU | |
| SCHEMBL20489830 | 0.77 | PRSS1 (0.58) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL7564632 | 0.76 | PLG (0.47) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL24358796 | 0.76 | PRSS1 (0.71) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL4078620 | 0.76 | LOXL2 (1.00) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL8542393 | 0.76 | PRSS1 (1.00) | PRSS1PRSS2PRSS3LOXL2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511721-B1 | GUANIDINO PHENYLALANIN COMPOUNDS USED AS UROKINASE INHIBITORS | WILEX AG (DE) | 2009-07-01 | — | — | EP | disclosed |