Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086554 | 0.78 | RXRA (0.46) | RXRARXRBRXRG | |
| SCHEMBL4517231 | 0.76 | RXRA (0.32) | RXRA | |
| SCHEMBL30573101 | 0.72 | RXRA (0.46) | RXRARXRBRXRG | |
| SCHEMBL26607136 | 0.72 | RXRA (0.46) | RXRARXRBRXRG | |
| SCHEMBL6666115 | 0.71 | RXRA (0.48) | RXRARXRBRXRG | |
| SCHEMBL6330023 | 0.71 | RXRA (0.48) | RXRARXRBRXRG | |
| SCHEMBL26607276 | 0.69 | PPARA (0.32) | — | |
| SCHEMBL4654263 | 0.68 | RXRA (0.37) | RXRARXRBRXRG | |
| SCHEMBL5706327 | 0.68 | RXRA (0.51) | RXRARXRBRXRG | |
| SCHEMBL6085848 | 0.68 | HTR2A (0.46) | RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696899-A1 | METHODS FOR TREATING RETINOID RESPONSIVE DISORDERS USING SELECTIVE INHIBITORS OF CYP26A AND CYP26B | ALLERGAN, INC. (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058301-A1 | METHODS FOR TREATING RETINOID RESPONSIVE DISORDERS USING SELECTIVE INHIBITORS OF CYP26A AND CYP26B | ALLERGAN, INC. (US) | 2005-06-30 | — | — | WO | disclosed |