Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.36 |
| ▸ | RXRG | P48443 | 2/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496270 | 0.93 | MAPT (0.38) | RXRARXRBRXRGHTR2AHTR2C | |
| SCHEMBL6086554 | 0.90 | RXRA (0.46) | RXRARXRBRXRGPOLA1CYP3A4 | |
| SCHEMBL6785200 | 0.87 | MAPT (0.46) | RXRAHTR2AHTR2CSLC6A4CYP3A4 | |
| SCHEMBL30573101 | 0.83 | RXRA (0.46) | RXRARXRBRXRGPOLA1CYP3A4 | |
| SCHEMBL26607136 | 0.83 | RXRA (0.46) | RXRARXRBRXRGPOLA1CYP3A4 | |
| SCHEMBL14016122 | 0.81 | RXRA (0.41) | RXRARXRBRXRGMAPTALDH1A1 | |
| SCHEMBL8293241 | 0.81 | RXRA (0.51) | RXRARXRBRXRGADORA3CHRM1 | |
| SCHEMBL9770756 | 0.81 | RXRA (0.41) | RXRARXRBRXRGADORA3CHRM1 | |
| SCHEMBL29518297 | 0.81 | RXRA (0.41) | RXRARXRBRXRGADORA3CHRM1 | |
| SCHEMBL14016123 | 0.79 | RXRA (0.45) | RXRARXRBRXRGMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485338-B1 | ALKOXY-SUBSTITUTED INDANONES AND THE PRODUCTION THEREOF | SYMRISE GMBH & CO KG (DE) | 2008-11-12 | — | — | EP | disclosed |
| EP-1485338-B1 | ALKOXY-SUBSTITUTED INDANONES AND THE PRODUCTION THEREOF | SYMRISE GMBH & CO KG (DE) | 2008-11-12 | — | — | EP | disclosed |
| US-7235699-B2 | Alkoxy-substituted indanes and the production thereof | SYMRISE GMBH & CO. KG (DE) | 2007-06-26 | — | — | US | disclosed |
| US-7235699-B2 | Alkoxy-substituted indanes and the production thereof | SYMRISE GMBH & CO. KG (DE) | 2007-06-26 | — | — | US | disclosed |
| US-7235699-B2 | Alkoxy-substituted indanes and the production thereof | SYMRISE GMBH & CO. KG (DE) | 2007-06-26 | — | — | US | disclosed |
| US-20050107476-A1 | preparation and use of the corresponding alkoxy-substituted indanones, important intermediates for the preparation of pharmaceutical products | SYMRISE GMBH & CO., KG (DE) | 2005-05-19 | — | — | US | disclosed |
| EP-1485338-A1 | ALKOXY-SUBSTITUTED INDANES AND THE PRODUCTION THEREOF | Symrise GmbH & Co. KG (DE) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003076379-A1 | ALKOXY-SUBSTITUTED INDANES AND THE PRODUCTION THEREOF | SYMRISE GMBH & CO. KG (DE) | 2003-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107476-A1 | preparation and use of the corresponding alkoxy-substituted indanones, important intermediates for the preparation of pharmaceutical products | CYP3A43, CYP1A2, CYP3A7 | RXRA 4471/4885RXRB 4199/4885RXRG 4149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.