⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604544 | 0.94 | TSHR (0.33) | — | |
| SCHEMBL5985622 | 0.85 | — | — | |
| SCHEMBL9438344 | 0.84 | TSHR (0.32) | — | |
| SCHEMBL23581523 | 0.80 | LMNA (0.43) | — | |
| SCHEMBL599901 | 0.76 | TSHR (0.47) | — | |
| SCHEMBL38014 | 0.76 | — | — | |
| SCHEMBL585568 | 0.76 | — | — | |
| SCHEMBL55157 | 0.76 | ALDH1A1 (0.30) | — | |
| SCHEMBL8813708 | 0.73 | — | — | |
| SCHEMBL231488 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110494143-B | Phospholipid derivatives and their use as pharmaceuticals | 捷克共和国科学院分子遗传学研究所 | 2022-12-20 | — | — | CN | claimed |
| CN-115135323-A | Pharmaceutical composition | 深圳市药欣生物科技有限公司 | 2022-09-30 | — | — | CN | claimed |
| EP-3606534-B1 | PHOSPHOLIPID DERIVATIVES AND THEIR USE AS MEDICAMENTS | USTAV MOLEKULARNI GENETIKY AV CR V V I (CZ) | 2021-05-12 | — | — | EP | claimed |
| US-20200102333-A1 | PHOSPHOLIPID DERIVATIVES AND THEIR USE AS MEDICAMENTS | Smart Brain s.r.o. (CZ) | 2020-04-02 | — | — | US | claimed |
| EP-3606534-A1 | PHOSPHOLIPID DERIVATIVES AND THEIR USE AS MEDICAMENTS | Ustav Molekularni Genetiky Akademie Ved CR, V.V.I. (CZ) | 2020-02-12 | — | — | EP | claimed |
| WO-2018184604-A1 | PHOSPHOLIPID DERIVATIVES AND THEIR USE AS MEDICAMENTS | USTAV MOLEKULARNI GENETIKY AV CR, V.V.I. (CZ) | 2018-10-11 | — | — | WO | claimed |
| US-20130087745-A1 | SOLUBLE PRECURSORS AND SOLUTION-BASED PROCESSES FOR PHOTOVOLTAICS | PRECURSOR ENERGETICS, INC. (US) | 2013-04-11 | — | — | US | claimed |
| US-8258325-B2 | For example diisononyl isosorbide; renewable plasticizers; replace phthalates which have health concerns | EVONIK OXENO GMBH (DE) | 2012-09-04 | — | — | US | claimed |
| EP-2064211-A1 | IMIDAZO[1,2-a]PYRIDINE HYDROXYMATE COMPOUNDS THAT ARE INHIBITORS OF HISTONE DEACETYLASE | S*Bio Pte Ltd (SG) | 2009-06-03 | — | — | EP | claimed |
| WO-2008036046-A1 | IMIDAZO[l,2-a]PYRIDINE HYDROXYMATE COMPOUNDS THAT ARE INHIBITORS OF HISTONE DEACETYLASE | S*BIO PTE LTD (SG) | 2008-03-27 | — | — | WO | claimed |
| US-6452009-B1 | A LARGE NUMBER OF RELATED ANALOGS ARE THEN SYNTHESIZED IN ORDER TO DEVELOP A STRUCTURE-ACTIVITY RELATIONSHIP | LION BIOSCIENCE AG (DE) | 2002-09-17 | — | — | US | claimed |
| US-12043762-B2 | Compositions and methods thereof | THE BOEING COMPANY (US) | 2024-07-23 | — | — | US | disclosed |
| US-12037329-B2 | SphK inhibitors and methods of making and using same | WASHINGTON UNIVERSITY (US) | 2024-07-16 | — | — | US | disclosed |
| CN-112689634-B | SMAD3 inhibitors | 莫扎制药有限公司 | 2024-07-16 | — | — | CN | disclosed |
| US-20240226342-A1 | REACTIVE OXYGEN SPECIES IMAGING AGENTS | WASHINGTON UNIVERSITY (US) | 2024-07-11 | — | — | US | disclosed |
| US-4206231-A | Hypoglycaemically active 2-alkyl- or -alkenyl-hydrazono propionic acid derivatives | BOEHRINGER MANNHEIM GMBH (DE) | 1980-06-03 | — | — | US | disclosed |
| EP-0004577-A2 | Process for preparing 2,2-dimethylol alkanals | BAYER AG (DE) | 1979-10-17 | — | — | EP | disclosed |
| EP-0001144-A1 | N-substituted 2-hydrazono-propionic acid derivatives, process for their preparation and pharmaceutical compositions containing them | Roche Diagnostics GmbH (DE) | 1979-03-21 | — | — | EP | disclosed |
| US-4122290-A | FORMALDEHYDE REACTED WITH AN ALDEHYDE, 2,2-DIMETHYLOLALKANE HYDROGENATED | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-24 | — | — | US | disclosed |
| US-4107136-A | Synthetic resin stabilizer comprising an organic phosphite and a carbonate | ARGUS CHEMICAL CORPORATION (US) | 1978-08-15 | — | — | US | disclosed |