SCHEMBL5706996

SCHEMBL5706996

CCOC(=O)/C(CC)=N\C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.45
SOAT1 P35610 1/20 0.44
ALDH1A1 P00352 5/20 0.42
MAPT P10636 3/20 0.41
LMNA P02545 3/20 0.40
HSD17B10 Q99714 1/20 0.40
GLO1 Q04760 1/20 0.40
APOBEC3A P31941 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
TSHR P16473 1/20 0.39
ALOX15 P16050 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
EGLN1 Q9GZT9 1/20 0.38
HCAR2 Q8TDS4 1/20 0.37
TRPA1 O75762 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706998 1.00 NPSR1 (0.45) NPSR1SOAT1ALDH1A1MAPTLMNA
SCHEMBL3836451 0.83 MAPT (0.40) NPSR1SOAT1ALDH1A1MAPTLMNA
SCHEMBL19168953 0.82 ALDH1A1 (0.48) NPSR1SOAT1ALDH1A1MAPTLMNA
SCHEMBL28622235 0.81 APOBEC3A (0.51) NPSR1SOAT1ALDH1A1MAPTLMNA
SCHEMBL26325159 0.81 APOBEC3A (0.51) NPSR1SOAT1ALDH1A1MAPTLMNA
SCHEMBL18590176 0.76 MAPT (0.46) NPSR1SOAT1ALDH1A1MAPTLMNA
SCHEMBL20350643 0.75 ALDH1A1 (0.46) NPSR1SOAT1ALDH1A1MAPTLMNA
SCHEMBL26386997 0.73 ALDH1A1 (0.43) NPSR1SOAT1ALDH1A1MAPTLMNA
SCHEMBL15341142 0.73
SCHEMBL18590175 0.73 APOBEC3A (0.38) NPSR1SOAT1ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1114836-B1 PROCESS FOR PRODUCING A RESIN COMPOSITION NAT INST OF ADVANCED IND SCIEN (JP) 2006-11-08 EP disclosed
US-6344516-B1 TRANSITION METAL COMPLEX CATALYST, OXIDATATIVE POLYMERIZATION OF PHENOL-CONTAINING VEGETABLE OIL NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2002-02-05 US disclosed
EP-1114836-A1 RESIN COMPOSITION AND PROCESS FOR PRODUCING THE SAME Japan as represented by Secretary of Agency of Industrial Science and Technology (JP) 2001-07-11 EP disclosed