Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL6129171 | 0.97 | CYP2D6 (0.32) | CYP2D6 | |
| SCHEMBL3837834 | 0.83 | — | — | |
| SCHEMBL3912391 | 0.79 | NPC1 (0.32) | — | |
| SCHEMBL28591684 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL4123671 | 0.75 | SIGMAR1 (0.33) | — | |
| SCHEMBL3921421 | 0.67 | HTT (0.31) | — | |
| SCHEMBL1956399 | 0.61 | — | — | |
| SCHEMBL5413667 | 0.61 | CYP2D6 (0.38) | CYP2D6 | |
| SCHEMBL6050677 | 0.61 | CYP2D6 (0.38) | CYP2D6 | |
| SCHEMBL9707 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701989-A2 | LOW K-FACTOR RIGID FOAM SYSTEMS | Bayer MaterialScience LLC (US) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005066233-A2 | LOW K-FACTOR RIGID FOAM SYSTEMS | BAYER MATERIALSCIENCE LLC (US) | 2005-07-21 | — | — | WO | disclosed |
| US-20050148677-A1 | Low K-factor rigid foam systems | BAYER MATERIALSCIENCE LLC | 2005-07-07 | — | — | US | disclosed |
| US-20020120026-A1 | CO-INITIATED POLYOLS USEFUL FOR THE PRODUCTION OF RIGID POLYURETHANE FOAMS | BAYER CORPORATION | 2002-08-29 | — | — | US | disclosed |
| US-5405886-A | Reacting polyols, water, isocyanate in presence of catalyst and quaternary ammonium salt | MILES INC. (US) | 1995-04-11 | — | — | US | disclosed |
| US-5252624-A | System for the production of toluene diisocyanate based flexible foams and the flexible foams produced therefrom | MILES INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0484749-A2 | Novel system for the production of toluene diisocyanate based flexible foams and the flexible foams produced therefrom | MILES INC. (US) | 1992-05-13 | — | — | EP | disclosed |