⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707187 | 1.00 | — | — | |
| SCHEMBL10782915 | 0.97 | — | — | |
| SCHEMBL24415263 | 0.76 | APLNR (0.30) | — | |
| SCHEMBL13734124 | 0.73 | — | — | |
| SCHEMBL27657661 | 0.71 | — | — | |
| SCHEMBL23542020 | 0.67 | — | — | |
| SCHEMBL25948776 | 0.67 | — | — | |
| SCHEMBL24416129 | 0.66 | FDPS (0.33) | — | |
| SCHEMBL15414766 | 0.64 | — | — | |
| SCHEMBL30733324 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718628-A1 | CINNAMIC AMIDES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Active Biotech AB (SE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005080362-A1 | CINNAMIC AMIDES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ACTIVE BIOTECH AB (SE) | 2005-09-01 | — | — | WO | disclosed |