Butadiene

Butadiene

SCHEMBL5707271

C=CC=C.OC1CCC(O)CC1

nearest known ligand 0.44

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Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
EPHX2 P34913 1/20 0.35
SHBG P04278 1/20 0.33
ESR2 Q92731 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1593359 0.78 TSHR (0.64) TSHREPHX2SHBGESR2
SCHEMBL102859 0.78
SCHEMBL3389566 0.78 TSHR (0.64) TSHREPHX2SHBGESR2
SCHEMBL28182 0.78
SCHEMBL2700308 0.78 TSHR (0.64) TSHREPHX2SHBGESR2
SCHEMBL275681 0.78
SCHEMBL8036941 0.78 TSHR (0.64) TSHREPHX2SHBGESR2
Vinyl Ether SCHEMBL65093 0.76 TSHR (0.37) TSHREPHX2
SCHEMBL12667255 0.76
SCHEMBL7845834 0.76 TSHR (0.37) TSHREPHX2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3951499-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, METHOD FOR FORMING CURED FILM, INTERLAYER INSULATION FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT Shin-Etsu Chemical Co., Ltd. (JP) 2022-02-09 EP disclosed
CN-105392765-B Compound, photosensitive composite, resist composition, resist film, solidification compound, resist composition for underlayer film and the resist lower membrane of phenolic hydroxy group DIC株式会社 2018-03-02 CN disclosed
CN-107108418-A Phenolic hydroxyl group-containing compound, composition containing same, and cured film thereof DIC株式会社 2017-08-29 CN disclosed
EP-1287985-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2006-10-11 EP disclosed