Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707346 | 1.00 | OPRD1 (0.41) | OPRD1MAPTABCC1MEN1KMT2A | |
| SCHEMBL10901099 | 0.70 | OPRD1 (0.50) | OPRD1MEN1KMT2ARAB9AMAOB | |
| SCHEMBL4559557 | 0.69 | OPRD1 (0.46) | OPRD1MEN1KMT2AOPRM1OPRK1 | |
| SCHEMBL2909561 | 0.68 | KMT2A (0.73) | MAPTMEN1KMT2ARAB9APOLB | |
| SCHEMBL2909559 | 0.68 | KMT2A (0.73) | MAPTMEN1KMT2ARAB9APOLB | |
| Hydrochloric Acid SCHEMBL11550501 | 0.67 | KMT2A (0.54) | OPRD1MEN1KMT2APOLBLMNA | |
| Piperazine SCHEMBL28235313 | 0.66 | KMT2A (0.71) | MAPTMEN1KMT2ARAB9APOLB | |
| Hydrochloric Acid SCHEMBL10853332 | 0.66 | KMT2A (0.71) | MAPTMEN1KMT2ARAB9APOLB | |
| Hydrochloric Acid SCHEMBL10853322 | 0.66 | KMT2A (0.71) | MAPTMEN1KMT2ARAB9APOLB | |
| SCHEMBL29557138 | 0.66 | SLC6A2 (0.48) | OPRD1MEN1KMT2ALMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718628-A1 | CINNAMIC AMIDES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Active Biotech AB (SE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005080362-A1 | CINNAMIC AMIDES, PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ACTIVE BIOTECH AB (SE) | 2005-09-01 | — | — | WO | disclosed |