Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901758 | 0.87 | OPRD1 (0.53) | OPRD1OPRM1CYP2D6CYP19A1TACR3 | |
| SCHEMBL10897567 | 0.83 | OPRD1 (0.57) | OPRD1OPRM1CYP2D6CYP19A1ALOX15 | |
| SCHEMBL10897511 | 0.80 | OPRD1 (0.48) | OPRD1OPRM1CYP2D6CYP19A1TACR3 | |
| SCHEMBL10898411 | 0.79 | OPRD1 (0.78) | OPRD1OPRM1CYP2D6CYP19A1MEN1 | |
| SCHEMBL7278992 | 0.73 | CYP2D6 (0.58) | OPRD1OPRM1CYP2D6CYP19A1SIGMAR1 | |
| SCHEMBL5754068 | 0.70 | TSHR (0.74) | EBPSIGMAR1MEN1DUSP3PTPN5 | |
| SCHEMBL5754075 | 0.70 | TSHR (0.74) | EBPSIGMAR1MEN1DUSP3PTPN5 | |
| SCHEMBL5707346 | 0.70 | OPRD1 (0.41) | OPRD1OPRM1CYP2D6TACR3MEN1 | |
| SCHEMBL5707349 | 0.70 | OPRD1 (0.41) | OPRD1OPRM1CYP2D6TACR3MEN1 | |
| SCHEMBL25083517 | 0.70 | CYP2D6 (0.54) | OPRD1OPRM1CYP2D6CYP19A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |