Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12036175 | 0.86 | CYP1A2 (0.46) | EPHX2EPHX1CYP1A2TDP1CA12 | |
| SCHEMBL191353 | 0.82 | LMNA (0.55) | EPHX2EPHX1CYP1A2TDP1LMNA | |
| SCHEMBL8947886 | 0.82 | LMNA (0.55) | EPHX2EPHX1CYP1A2TDP1LMNA | |
| SCHEMBL12036169 | 0.81 | EPHX2 (0.42) | EPHX2EPHX1CYP1A2TDP1CA12 | |
| Hydrochloric Acid SCHEMBL1835887 | 0.80 | LMNA (0.53) | EPHX2EPHX1CYP1A2TDP1LMNA | |
| SCHEMBL190928 | 0.79 | CYP1A2 (0.48) | EPHX2EPHX1CYP1A2TDP1RIPK1 | |
| SCHEMBL18214970 | 0.78 | EPHX2 (0.43) | EPHX2EPHX1CYP1A2TDP1RIPK1 | |
| SCHEMBL28435105 | 0.78 | CA12 (0.41) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL18711893 | 0.77 | CYP1A2 (0.46) | EPHX2EPHX1CYP1A2TDP1RIPK1 | |
| SCHEMBL11850495 | 0.77 | CYP1A2 (0.50) | EPHX2EPHX1CYP1A2TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020439-B1 | CETP ACTIVITY INHIBITORS | JAPAN TOBACCO INC (JP) | 2006-08-30 | — | — | EP | claimed |