Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704630 | 0.78 | CYP1A2 (0.44) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL2206284 | 0.75 | ALDH1A1 (0.33) | EPHX2EPHX1 | |
| SCHEMBL529492 | 0.74 | — | — | |
| SCHEMBL329321 | 0.72 | CYP1A2 (0.52) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL8947886 | 0.71 | LMNA (0.55) | EPHX2EPHX1CYP1A2TDP1 | |
| SCHEMBL191353 | 0.71 | LMNA (0.55) | EPHX2EPHX1CYP1A2TDP1 | |
| SCHEMBL24568178 | 0.71 | EPHX2 (0.38) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL4550276 | 0.70 | SMN1; SMN2 (0.52) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL21325280 | 0.70 | CYP1A2 (0.50) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL83783 | 0.70 | CYP1A2 (0.50) | EPHX2EPHX1CYP1A2TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020439-B1 | CETP ACTIVITY INHIBITORS | JAPAN TOBACCO INC (JP) | 2006-08-30 | — | — | EP | claimed |