Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.57 |
| ▸ | CTSS | P25774 | 6/20 | 0.57 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842382 | 1.00 | CTSK (0.57) | CTSKCTSSCTSBCTSLKLK5 | |
| SCHEMBL21457973 | 0.88 | CTSS (0.56) | CTSKCTSSCTSBCTSLKLK5 | |
| SCHEMBL21457987 | 0.88 | CTSS (0.56) | CTSKCTSSCTSBCTSLKLK5 | |
| SCHEMBL3842768 | 0.88 | CTSS (0.56) | CTSKCTSSCTSBCTSLKLK5 | |
| SCHEMBL5850035 | 0.87 | CTSK (0.57) | CTSKCTSSCTSBCTSLKLK5 | |
| SCHEMBL3841362 | 0.87 | CTSK (0.57) | CTSKCTSSCTSBCTSLKLK5 | |
| SCHEMBL27640245 | 0.87 | CTSK (0.57) | CTSKCTSSCTSBCTSLKLK5 | |
| SCHEMBL20028163 | 0.84 | CTSK (0.55) | CTSKCTSSCTSBCTSLKLK5 | |
| SCHEMBL3842569 | 0.83 | CTSK (0.52) | CTSKCTSSCTSBCTSLKLK5 | |
| SCHEMBL3757945 | 0.83 | CTSK (0.58) | CTSKCTSSCTSBCTSLKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692098-A1 | ALPHA-KETOAMIDE DERIVATIVE, AND PRODUCTION METHOD AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005056519-A1 | ALPHA-KETOAMIDE DERIVATIVE, AND PRODUCTION METHOD AND USE THEREOF | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2005-06-23 | — | — | WO | disclosed |