SCHEMBL5707874

SCHEMBL5707874

O=C(CCn1nc2ccccc2n1)OCCO

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 1/20 0.41
▸ FNTB P49356 1/20 0.41
▸ TDP1 Q9NUW8 2/20 0.41
▸ ALDH1A1 P00352 6/20 0.39
▸ RECQL P46063 1/20 0.38
▸ MAPT P10636 2/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ TOP2A P11388 2/20 0.37
▸ GAA P10253 2/20 0.37
▸ LMNA P02545 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23880027 0.84 GAA (0.52) TDP1ALDH1A1MAPTL3MBTL1TOP2A
SCHEMBL23880030 0.83 ALDH1A1 (0.54) ALDH1A1MAPTTOP2ALMNAHSD17B10
SCHEMBL25588376 0.81 LMNA (0.54) ALDH1A1RECQLMAPTL3MBTL1GAA
SCHEMBL25588403 0.81 LMNA (0.54) ALDH1A1RECQLMAPTL3MBTL1GAA
SCHEMBL25588398 0.81 LMNA (0.54) ALDH1A1RECQLMAPTL3MBTL1GAA
SCHEMBL25588394 0.81 LMNA (0.54) ALDH1A1RECQLMAPTL3MBTL1GAA
SCHEMBL25588385 0.81 LMNA (0.54) ALDH1A1RECQLMAPTL3MBTL1GAA
SCHEMBL23880045 0.81 LMNA (0.54) ALDH1A1RECQLMAPTL3MBTL1GAA
SCHEMBL25588389 0.81 LMNA (0.54) ALDH1A1RECQLMAPTL3MBTL1GAA
SCHEMBL23880026 0.79 HSD17B10 (0.49) ALDH1A1MAPTGAAKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105849210-B Dispersants having multiple aromatic imide anchoring groups 路博润先进材料公司 2019-12-13 — — CN disclosed
EP-1089809-B1 POLYURETHANE DISPERSANTS LUBRIZOL CORP (US) 2006-10-18 — — EP disclosed
CN-1215900-C Polyurethane dispersants LOUBORUN CORP (US) 2005-08-24 — — CN disclosed
US-6509409-B1 A dispersant comprising the addition product of a polyisocyanate having an average functionality of from 2 to 10 and one or more poly(oxyalkylene carbonyl) chains (POAC chain) such as those containing a POAC chain derived from AVECIA LIMITED (GB) 2003-01-21 — — US disclosed
EP-0956153-B1 DISPERSING AGENT EFKA ADDITIVES B V (NL) 2002-10-02 — — EP disclosed
CN-1308560-A Polyurethane dispersants AVECIA LTD (GB) 2001-08-15 — — CN disclosed
EP-1089809-A1 POLYURETHANE DISPERSANTS Avecia Limited (GB) 2001-04-11 — — EP disclosed
WO-1999056864-A1 POLYURETHANE DISPERSANTS AVECIA LIMITED (GB) 1999-11-11 — — WO disclosed
US-5882393-A REACTION PRODUCT OF POLYISOCYANATES WITH A COMPOUND OF RING STRUCTURE WITH AT LEAST ONE NITROGEN ATOM IN RING; LACQUER EFKA CHEMICALS B.V. (NL) 1999-03-16 — — US disclosed
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