Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.31 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5707963 | 0.99 | GAA (0.44) | GAARAD52KCNH2KDM4EMAPT | |
| SCHEMBL5707962 | 0.88 | MAPT (0.40) | GAARAD52KCNH2KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL5707969 | 0.87 | KDM4E (0.39) | GAARAD52KCNH2KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL5707958 | 0.80 | GAA (0.52) | GAARAD52KCNH2KDM4EMAPT | |
| SCHEMBL5707910 | 0.77 | GAA (0.50) | GAARAD52KCNH2KDM4EMAPT | |
| SCHEMBL5707930 | 0.77 | GAA (0.58) | GAARAD52KCNH2KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL5707922 | 0.76 | GAA (0.49) | GAARAD52KCNH2KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL5707956 | 0.76 | GAA (0.56) | GAARAD52KCNH2KDM4EMAPT | |
| SCHEMBL5203962 | 0.75 | GAA (0.65) | GAARAD52KCNH2KDM4EMAPT | |
| SCHEMBL2127202 | 0.74 | GAA (0.37) | GAARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1462445-B1 | Paraphenyldiamine derivatives concisting of a cyclic diaza group substituted by a cationic radical and use of these derivatives for dyeing keratin fibres | OREAL (FR) | 2006-10-18 | — | — | EP | claimed |
| EP-1462445-B1 | Paraphenyldiamine derivatives concisting of a cyclic diaza group substituted by a cationic radical and use of these derivatives for dyeing keratin fibres | OREAL (FR) | 2006-10-18 | — | — | EP | disclosed |