Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | GFER | P55789 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | RAD52 | P43351 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5707970 | 0.99 | MAPT (0.51) | MAPTKDM4EGFERGAASMN1; SMN2 | |
| SCHEMBL5707917 | 0.95 | MAPT (0.48) | MAPTKDM4EGFERGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5707945 | 0.94 | MAPT (0.47) | MAPTKDM4EGFERGAASMN1; SMN2 | |
| SCHEMBL6151485 | 0.92 | MAPT (0.50) | MAPTKDM4EGFERGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6413349 | 0.91 | MAPT (0.49) | MAPTKDM4EGFERGAASMN1; SMN2 | |
| SCHEMBL5707930 | 0.83 | GAA (0.58) | MAPTKDM4EGFERGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5707956 | 0.82 | GAA (0.56) | MAPTKDM4EGFERGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5829351 | 0.79 | ADRA2C (0.49) | MAPTKDM4EGAASMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL5707958 | 0.79 | GAA (0.52) | MAPTKDM4EGFERGAASMN1; SMN2 | |
| SCHEMBL6151900 | 0.76 | GFER (0.52) | MAPTKDM4EGFERGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1462445-B1 | Paraphenyldiamine derivatives concisting of a cyclic diaza group substituted by a cationic radical and use of these derivatives for dyeing keratin fibres | OREAL (FR) | 2006-10-18 | — | — | EP | claimed |
| EP-1462445-B1 | Paraphenyldiamine derivatives concisting of a cyclic diaza group substituted by a cationic radical and use of these derivatives for dyeing keratin fibres | OREAL (FR) | 2006-10-18 | — | — | EP | disclosed |